The midfielder Hargreaves still not fit to play as he has battle tendinitis in his knee for more than two years, allowing him just one appearance as a substitute in the first team in that period.
Meanwhile, new Portuguese signing Bebe was also overlooked as United surprisingly named a squad of just 24 players when they could have added one more.
Hargreaves and Bebe could be included in a new squad list for the knockout stages if Manchester United make it through from group C which also features Glasgow Rangers, Valencia and Bursaspor.
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